Croscarmellose Sodium
Croscarmellose Sodium is cross-linked sodium carboxymethyl methyl cellulose without use of any cross-linking agent. It is insoluble, white to greyish white free flowing powder.
In compressed tablets croscarmellose sodium will prove to be an excellent disintegrant Inclusion of 1 - 3 % concentration of tablet weight is the typical range is mostly sufficient.
Good water uptake, Rapid swelling, Relatively long fiber length for effective fluid channeling excellent long term dissolution stability, Dissolution / disintegration independent to tablet hardness are the feature and benefits of croscarmellose sodium.